Fig. 7: Cross-stain comparison of tissue regions with and without CTTA. | npj Digital Medicine

Fig. 7: Cross-stain comparison of tissue regions with and without CTTA.

From: Uncertainty-aware and causal test-time adaptive foundation model for robust colorectal cancer pathology diagnosis

Fig. 7

Rows show the same region under different staining protocols (H& E, normalized H& E, PAS, synthetic variants). Columns display the original patch, Grad-CAM from the baseline, Grad-CAM from the CTTA-enhanced model, and expert ROIs. Baseline focus varies across stains and often attends to artifacts, whereas CTTA consistently highlights diagnostically relevant glandular and epithelial structures, aligning more closely with expert annotations.

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