Table 6 Comparison of pathway enrichment scores for COVID-19 vs. influenza using different analysis methods
Pathway | ssGSEA (all data) | GSVA (all data) | ssGSEA (no RSV) |
|---|---|---|---|
Type I IFN response | − 2.3 | − 2.1 | − 2.4 |
IL-6/STAT3 signaling | + 2.0 | + 1.9 | + 2.1 |
T-cell activation | − 1.8 | − 1.7 | − 1.9 |
AP-1/MAPK pathway | + 1.7 | + 1.6 | + 1.8 |
