Fig. 4: Associations of OPRS and healthy lifestyle factors with all-cause mortality in Cox models.

The models were adjusted for age, sex. a Training cohort. b Internal test cohort. OPRS, Obesity-related polygenic risk score. Lifestyle included 4 lifestyle factors (never smoking, no or moderate alcohol consumption, physical activity, and healthy diet). Participants scored 1 if they met the criterion for a healthy lifestyle and 0 otherwise. This graph was generated by R.