Table 1 Baseline demographic, clinical, and ECG-derived metrics of participants in the S-Patch and Memo Patch registries

From: Wearable device derived electrocardiographic age and its association with atrial fibrillation

 

S-Patch Registry

Memo Patch Registry

 
 

N

mean ± SD or n (%)

N

mean ± SD or n (%)

P-value

Total Sample Count

1502

 

529

  

AF status

1502

 

529

 

<0.001

None

 

285 (19%)

 

505 (95%)

 

Atrial fibrillation

 

1217 (81%)

 

24 (5%)

 

AI-ECG metrics

1502

 

529

  

AI-ECG age (years)

 

60.4 ± 9.3

 

58.2 ± 8.8

<0.001

AI-ECG age gap (years)

 

−1.8 ± 12.4

 

-9.2 ± 11.0

<0.001

Demographics

Age (years)

1502

62.2 ± 11.0

529

67.4 ± 9.6

<0.001

Sex

1502

 

529

 

<0.001

Male

 

993 (66%)

 

152 (29%)

 

Female

 

509 (34%)

 

377 (71%)

 

BMI (kg/m²)

1500

24.5 ± 4.0

524

24.2 ± 3.4

0.052

Blood pressure

1500

 

528

  

Systolic BP (mmHg)

 

126.8 ± 15.2

 

130.5 ± 16.5

<0.001

Diastolic BP (mmHg)

 

74.4 ± 11.2

 

73.5 ± 11.3

0.127

Comorbidities

1500

 

528

  

Heart failure

 

194 (13%)

 

25 (5%)

<0.001

Hypertension

 

828 (55%)

 

347 (66%)

<0.001

Diabetes mellitus

 

272 (18%)

 

144 (27%)

<0.001

Prior stroke or TIA

 

146 (10%)

 

47 (9%)

0.636

Risk Scores

CHA₂DS₂-VASc score

1500

2.0 ± 1.4

528

2.9 ± 1.1

<0.001

HAS-BLED score

1499

1.2 ± 0.9

NA

NA

NA

Smoking status

1500

 

527

 

0.011

 None

 

1186 (79%)

 

446 (84%)

 

 Mild

 

175 (12%)

 

51 (10%)

 

 Severe

 

139 (9%)

 

30 (6%)

 

Drinking status

1500

 

527

 

<0.001

 None

 

1094 (73%)

 

436 (82%)

 

 Mild

 

71 (5%)

 

57 (11%)

 

 Severe

 

335 (22%)

 

34 (6%)

 
  1. Data are presented as mean ± standard deviation (SD) for continuous variables and number (%) for categorical variables. P-values refer to comparisons between S-Patch and Memo Patch registries (Welch’s t-test for continuous variables; χ² test for categorical variables). AI-ECG age refers to the model-predicted electrophysiological age derived from sinus rhythm segments; AI-ECG age gap is calculated as AI-ECG age minus chronological age. AF burden denotes the percentage of monitoring time spent in atrial fibrillation. Risk Scores: CHA₂DS₂-VASc (Congestive heart failure, Hypertension, Age ≥75 [doubled], Diabetes mellitus, Stroke/TIA [doubled], Vascular disease, Age 65–74, Sex category [female]); HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history, Labile INR, Elderly, Drugs/alcohol concomitantly. Bold values indicate statistical significance (p < 0.05).
  2. AF atrial fibrillation, BMI body mass index, BP blood pressure, HF heart failure, TIA transient ischemic attack, NA not available.