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Validating an adaptive digital assessment of youth mental health needs: a cross-sectional study
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  • Published: 12 February 2026

Validating an adaptive digital assessment of youth mental health needs: a cross-sectional study

  • William Capon1,
  • Ian B. Hickie1,
  • Mathew Varidel1,
  • Haley M. LaMonica1,
  • Luke J. Borgnolo1,
  • Jacob J. Crouse1,
  • Elizabeth M. Scott1 &
  • …
  • Frank Iorfino1 

npj Digital Medicine , Article number:  (2026) Cite this article

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Diseases
  • Health care
  • Medical research
  • Psychology

Abstract

Digital mental health assessments can effectively link young people to appropriate health services. Current approaches often lack personalization, failing to recognize the complex and multidimensional needs of young people. 1734 young people aged 12–25 years completed seven standardized measures (49 items) using a digital health assessment tool while receiving mental health care. A multidimensional computerized adaptive test (MCAT) was developed to predict scores on seven standardized scales, spanning clinical symptoms, suicidality, functioning, and alcohol use. Different adaptive tests were simulated under various stopping criteria configurations. Ten-fold cross-validation was performed to determine the accuracy and efficiency of the multidimensional assessment. By administering a personalized subset of items to each individual, the average number of assessment items could be reduced by 69% while maintaining excellent agreement with full-length scores for suicidality (ICC = 0.96), anxiety (ICC = 0.92), and alcohol use (ICC = 0.91), and good agreement for psychological distress (ICC = 0.88), functioning (ICC = 0.86), psychosis (ICC = 0.78), and mania (ICC = 0.75). Estimated average assessment time decreased from 10.5 minutes to under 3.3 minutes (49 items reduced to 15.3 items, per person, with mean absolute agreement ICC = 0.87). This adaptive digital assessment can screen across key domains to identify mental health needs and complexity in youth mental health, leading to rapid decisions about treatment needs and care pathways.

Data availability

The data that support the findings of this study are available from Innowell Pty Ltd, but restrictions apply to the availability of these data, which were used under licence for the current study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of Innowell Pty Ltd.

Code availability

The underlying code for this study is under formal intellectual property review by the University of Sydney and is therefore not publicly available.

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Acknowledgements

WC extends his gratitude to Samuel McLeod for guidance related to cross-validation. The funding sources of this study had no role in the design, data collection, data analysis, and reporting of this study. This work was supported by the Medical Research Future Fund Applied Artificial Intelligence in Health Care grant [MRFAI000097]. W.C. was supported by the Australian Government Research Training Program (RTP) Scholarship. J.J.C. was supported by an NHMRC Emerging Leadership Fellowship (2008197). I.B.H. was supported by an NHMRC Research Fellowship (511921). HML is supported by the Bill & Patricia Richie Foundation and a philanthropic funding donor affected by mental health who wishes to remain anonymous. F.I. was supported by an NHMRC EL1 Investigator Grant (GNT2018157).

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Authors and Affiliations

  1. Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia

    William Capon, Ian B. Hickie, Mathew Varidel, Haley M. LaMonica, Luke J. Borgnolo, Jacob J. Crouse, Elizabeth M. Scott & Frank Iorfino

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Contributions

W.C. and F.I. conceptualized the project. W.C. conceptualized and conducted the analysis. M.V. reviewed the analysis and provided ongoing statistical guidance. All authors interpreted the results and provided insights. W.C. wrote the initial draft of the manuscript. WC created the figures, tables, and supplementary material. All authors (W.C., I.B.H., M.V., H.M.L., L.J.B., J.J.C., E.M.S., F.I.) provided useful and significant changes to the first draft of the manuscript.

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Correspondence to William Capon.

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Competing interests

I.B.H. is a Professor of Psychiatry and the Co-Director of Health and Policy, Brain and Mind Centre, University of Sydney. He has led major public health and health service development in Australia, particularly focusing on early intervention for young people with depression, suicidal thoughts and behaviors and complex mood disorders. He is active in the development through codesign, implementation and continuous evaluation of new health information and personal monitoring technologies to drive highly-personalized and measurement-based care. He holds a 3.2% equity share in Innowell Pty Ltd., which is focused on the digital transformation of mental health services. E.M.S. is a Principal Research Fellow at the Brain and Mind Centre, University of Sydney, a Consultant Psychiatrist and Adjunct Clinical Professor at the School of Medicine, University of Notre Dame. She previously served as the Discipline Leader for Adult Mental Health at Notre Dame until January 2025. In addition, she is a member of Medibank’s Medical and Mental Health Reference Groups. A/Prof Scott has also delivered educational seminars on the clinical management of depressive disorders, receiving honoraria from pharmaceutical companies including Servier, Janssen, and Eli Lilly. Moreover, she has contributed to a national advisory board for Pfizer’s antidepressant Pristiq and served as the National Coordinator for an antidepressant trial sponsored by Servier. All other authors declare no competing interests.

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Capon, W., Hickie, I.B., Varidel, M. et al. Validating an adaptive digital assessment of youth mental health needs: a cross-sectional study. npj Digit. Med. (2026). https://doi.org/10.1038/s41746-026-02374-2

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  • Received: 21 July 2025

  • Accepted: 13 January 2026

  • Published: 12 February 2026

  • DOI: https://doi.org/10.1038/s41746-026-02374-2

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