Fig. 6: Associations of asthma subphenotypes with adverse events.

Hazard ratios and 95% confidence intervals (horizontal lines) are shown for six clinical indicators of asthma severity, based on recurrent event analyses. Each panel represents a separate comparison: a severe versus non-severe asthma and b high versus low exacerbator clusters among individuals with severe asthma. Vertical dashed lines indicate a hazard ratio of 1 (no association).