Abstract
Digital front doors combining symptom assessment and self-triage are increasingly used, yet real-world evidence on their clinical integration remains limited. This prospective post-market clinical follow-up evaluated a clinical decision support system embedded in routine care within a large private healthcare network. Adults completed a structured symptom assessment before consultation, and both participants and physicians completed predefined questionnaires. Treating physicians generally judged the urgency advice and assessment report to be appropriate. When the report was reviewed before the consultation, physicians reported greater preparedness and perceived efficiency gains. Participants generally reported complete symptom capture and improved preparedness. These findings provide prospective real-world evidence that a symptom assessment CDSS can generate appropriate outputs in routine care and may support both patient preparation and clinician workflow when integrated into practice.
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This work was supported by the Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung) through the European Union-financed NextGenerationEU program under grant number 16KISA100K, project PATH—“Personal Mastery of Health and Wellness Data.”
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A.L. is employed by Ada Health. A.P., N.K., M.S. and T.M. are former employees of Ada Health. S.G. and F.C. are consultants for Ada Health, and S.G., T.M., A.P. and F.C. hold share options in the company. S.G. declares a nonfinancial interest as an Advisory Group member of the EY-coordinated “Study on Regulatory Governance and Innovation in the field of Medical Devices” conducted on behalf of the Directorate-General for Health and Food Safety (SANTE) of the European Commission. S.G. declares the following competing financial interests: he has or has had consulting relationships with Una Health GmbH, Lindus Health Ltd., Flo Ltd, ICURA ApS, Rock Health Inc., Thymia Ltd., FORUM Institut für Management GmbH, High-Tech Gründerfonds Management GmbH, Prova Health Ltd, Directorate-General for Research and Innovation Of the European Commission. T.M. declares the following competing financial interests: he has or has had consulting relationships with Suvera & iPlato Healthcare. F.C. declares the following competing financial interests: she has or has had consulting relationships with Flo Ltd and Amboss SE. The remaining authors declare no competing interests.
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Pimenta, A., Kini, N., Cotte, F. et al. Appropriateness and utility of a clinical decision support system at the digital front door. npj Digit. Med. (2026). https://doi.org/10.1038/s41746-026-02711-5
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DOI: https://doi.org/10.1038/s41746-026-02711-5
