Extended Data Fig. 7: Intravital three-photon microscopy images of MOTEs in mouse brains.
From: A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice
a, MOTE 1 inside mouse 1 on day 128, b, MOTE 1 inside mouse 2 on day 132, c, MOTE 2 inside mouse 3 on day 8 (left) and day 127 (right). Auto-fluorescence was detected in 525 ± 25 nm by using 1300 nm excitation source. The black arrows (on the sides of the bottom figures) indicate the brain surface where the top of the z-axis is the bottom of the implanted cover glass; sometimes there is a space between the cover glass and the brain surface (for example, MOTE 2 inside mouse 3 on day 8 shown in c). All scale bars (yellow horizontal lines) are 100 µm and we have measured six different MOTEs over three different dates with similar findings (also see Supplementary Videos 4–7).
