Abstract
Continuous and precise monitoring of physiological signals via epidermal sensors could be of use in the development of personalized healthcare. However, the practical deployment of such sensors is hindered by the need for bulky batteries and limitations in data transfer. Here we report a battery-free epidermal network that is wirelessly interconnected through a wearable metamaterial and can provide continuous, high-fidelity biosensing. The network separates the power transfer (13.56 MHz) and data communication (2.4 GHz) channels through a dual-mode metamaterial textile, providing efficient wireless power transfer and low-latency data communication. We use a smartphone as a hub to wirelessly deliver power to and acquire biological signals from multiple networked epidermal sensors mediated by the metamaterial, which is integrated in clothing. The network can continuously monitor systolic blood pressure, including in dynamic environments such as during exercise.
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Data availability
Source data are provided with this paper. All other relevant data that support the findings of this study are available from the corresponding authors upon reasonable request.
References
Xu, S., Jayaraman, A. & Rogers, J. A. Skin sensors are the future of health care. Nature 571, 319–321 (2019).
Chu, B., Burnett, W., Chung, J. W. & Bao, Z. Bring on the bodynet. Nature 549, 328–330 (2017).
Choi, Y. S. et al. A transient, closed-loop network of wireless, body-integrated devices for autonomous electrotherapy. Science 376, 1006–1012 (2022).
World Health Organisation. Hypertension—fact sheet (World Health Organisation, 2021); http://www.who.int/news-room/fact-sheets/detail/hypertension
US Food and Drug Administration. High blood pressure—understanding the silent killer (US Food and Drug Administration, 2024); http://www.fda.gov/drugs/special-features/high-blood-pressure-understanding-silent-killer
Staessen, J. A., Wang, J., Bianchi, G. & Birkenhäger, W. H. Essential hypertension. Lancet 361, 1629–1641 (2003).
Chung, H. U. et al. Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units. Nat. Med. 26, 418–429 (2020).
Tucker, S., Hanna, J. & Gutruf, P. Wearable devices for continuous monitoring of biosignals: challenges and opportunities. APL Bioeng. 6, 021502 (2022).
Franklin, D. et al. Synchronized wearables for the detection of haemodynamic states via electrocardiography and multispectral photoplethysmography. Nat. Biomed. Eng. 7, 1229–1241 (2023).
Niu, S. et al. A wireless body area sensor network based on stretchable passive tags. Nat. Electron. 2, 361–368 (2019).
Stuart, T. et al. Biosymbiotic, personalized, and digitally manufactured wireless devices for indefinite collection of high-fidelity biosignals. Sci. Adv. 7, eabj3269 (2021).
Han, S. et al. Battery-free, wireless sensors for full-body pressure and temperature mapping. Sci. Transl. Med. 10, eaan4950 (2018).
Chung, H. U. et al. Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care. Science 363, eaau0780 (2019).
Hajiaghajani, A. et al. Textile-integrated metamaterials for near-field multibody area networks. Nat. Electron. 4, 808–817 (2021).
Lin, R. et al. Wireless battery-free body sensor networks using near-field-enabled clothing. Nat. Commun. 11, 444 (2020).
Tian, X. et al. Wireless body sensor networks based on metamaterial textiles. Nat. Electron. 2, 243–251 (2019).
Tian, X., Zeng, Q., Nikolayev, D. & Ho, J. S. Conformal propagation and near-omnidirectional radiation with surface plasmonic clothing. IEEE Trans. Antennas Propag. 68, 7309–7319 (2020).
Asada, H. H., Shaltis, P., Reisner, A., Rhee, S. & Hutchinson, R. C. Mobile monitoring with wearable photoplethysmographic biosensors. IEEE Eng. Med. Biol. Mag. 22, 28–40 (2003).
Lont, M., Milosevic, D. & van Roermund, A. Wake-Up Receiver Based Ultra-Low-Power WBAN (Springer, 2014).
Li, J., Dong, Y., Park, J. H. & Yoo, J. Body-coupled power transmission and energy harvesting. Nat. Electron. 4, 530–538 (2021).
Saadeh, W., Altaf, M. A. B., Alsuradi, H. & Yoo, J. A 1.1-mW ground effect-resilient body-coupled communication transceiver with pseudo OFDM for head and body area network. IEEE J. Solid-State Circuits 52, 2690–2702 (2017).
Tran, T. V., Dang, N. T. & Chung, W.-Y. Battery-free smart-sensor system for real-time indoor air quality monitoring. Sens. Actuators B 248, 930–939 (2017).
ams. SL900A EPC Class 3 Sensory Tag Chip—for automatic data logging (AMS Premstaetten, 2018); https://look.ams-osram.com/m/7123a0170551e6e/original/SL900A-DS000294.pdf
Bluetooth Special Interest Group. Bluetooth core specification v.4.0 (Bluetooth SIG, 2010); https://www.bluetooth.com/specifications/specs
LaCost, E. Battery-less NFC/RFID Temperature Sensing Patch. Report No. SLOA212A (Texas Instruments, 2016).
Luo, Y. et al. Technology roadmap for flexible sensors. ACS nano 17, 5211–5295 (2023).
Bluetooth Special Interest Group. Bluetooth core specification v.5.2 (Bluetooth SIG, 2019); https://www.bluetooth.com/specifications/specs
Nordic Semiconductor. nRF Connect for Desktop v.3.6.1. GitHub https://github.com/NordicSemiconductor/pc-nrfconnect-launcher/releases/tag/v3.6.1 (2020).
Wang, T.-W., Zhang, H. & Lin, S.-F. Influence of capacitive coupling on high-fidelity non-contact ECG measurement. IEEE Sensors J. 20, 9265–9273 (2020).
Yeo, W.-H. et al. Multifunctional epidermal electronics printed directly onto the skin. Adv. Mater. 25, 2773–2778 (2013).
Heikenfeld, J. et al. Wearable sensors: modalities, challenges, and prospects. Lab on Chip 18, 217–248 (2018).
Kim, J. et al. Miniaturized battery-free wireless systems for wearable pulse oximetry. Adv. Funct. Mater.27, 1604373 (2017).
McMullen, M. K., Whitehouse, J. M., Shine, G., Whitton, P. A. & Towell, A. The immediate and short-term chemosensory impacts of coffee and caffeine on cardiovascular activity. Food Funct. 2, 547–554 (2011).
Bain, A. R., Drvis, I., Dujic, Z., MacLeod, D. B. & Ainslie, P. N. Physiology of static breath holding in elite apneists. Exp. Physiol. 103, 635–651 (2018).
Bland, J. M. & Altman, D. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 327, 307–310 (1986).
Association for the Advancement of Medical Instrumentation. Cardiac Monitors, Heart Rate Meters, and Alarms. Report No. ANSI/AAMI EC13 (Association for the Advancement of Medical Instrumentation, 2002).
Consumer Technology Association Physical activity monitoring for heart rate. CTA Standard 2065, 1–21 (2018).
International Organization for Standardization. Medical Electrical Equipment—Part 2-61: Particular Requirements for Basic Safety and Essential Performance of Pulse Oximeter Equipment. Report No. ISO 80601-2-61:2017 (International Organization for Standardization, 2017).
US Food and Drug Administration. Pulse Oximeters—Premarket Notification Submissions [510(k)s]: Guidance for Industry and Food and Drug Administration Staff (US Food and Drug Administration, 2013); http://www.fda.gov/media/72470/download
Spaccarotella, C. et al. Assessment of non-invasive measurements of oxygen saturation and heart rate with an apple smartwatch: comparison with a standard pulse oximeter. J. Clin. Med. 11, 1467 (2022).
Buxi, D., Redoute, J.-M. & Yuce, M. R. A survey on signals and systems in ambulatory blood pressure monitoring using pulse transit time. Physiol. Meas. 36, R1 (2015).
Chan, C. H., Poon, C. C. Y., Wong, R. C. S. & Zhang, Y. T. A hybrid body sensor network for continuous and long-term measurement of arterial blood pressure. In Proc. 4th IEEE/EMBS International Summer School and Symposium on Medical Devices and Biosensors 121–123 (IEEE, 2007).
Espina, J. et al. Wearable body sensor network towards continuous cuff-less blood pressure monitoring. In Proc. 5th International Summer School and Symposium on Medical Devices and Biosensors 28–32 (IEEE, 2008).
Li, J. et al. Thin, soft, wearable system for continuous wireless monitoring of artery blood pressure. Nat. Commun. 14, 5009 (2023).
Takahashi, H., Saito, K. & Hishiki, Y. Validation of Omron HEM-7600T, a wearable device for monitoring blood pressure, in the general population without arrhythmias. Blood Press. Monit. 26, 156–159 (2021).
Association for the Advancement of Medical Instrumentation. American National Standard for Electronic or Automated Sphygmomanometers. Report No. ANSI/AAMI SP10 (Association for the Advancement of Medical Instrumentation, 2002).
Kario, K. Nocturnal hypertension: new technology and evidence. Hypertension 71, 997–1009 (2018).
Kario, K. et al. Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives: a prospective study. Circulation 107, 1401–1406 (2003).
Salles, G. F. et al. Prognostic effect of the nocturnal blood pressure fall in hypertensive patients: the ambulatory blood pressure collaboration in patients with hypertension (ABC-H) meta-analysis. Hypertension 67, 693–700 (2016).
Assaf, Y. et al. Peak systolic blood pressure during the exercise test: reference values by sex and age and association with mortality. Hypertension 77, 1906–1914 (2021).
Hedman, K. et al. Peak exercise sbp and future risk of cardiovascular disease and mortality. J. Hypertens. 40, 300 (2022).
Carlen, A. et al. Exercise systolic blood pressure indexed to work rate predicts future risk of incident stroke. Eur. J. Prev. Cardiol. 30, zwad125–248 (2023).
Acknowledgements
X.T. acknowledges funding support from the National Natural Science Foundation of China (grant number 62501361), the Guangdong Basic and Applied Basic Research Foundation (grant number 2025A1515010122) and the Shenzhen Science and Technology Program (grant number JCYJ20250604180342057). X.T. also acknowledges funding support from the Tsinghua SIGS. P.G. acknowledges support from the Moore Foundation (019797-00001) and the Technology and Research Initiative Fund (TRIF). S.A.K. thanks the Agency for Science, Technology and Research (A*STAR) for its support of our research through the SINGA fellowship program. K.A.K. acknowledges support from a NIH Infection and Inflammation as Drivers of Aging (IIDA) training grant (1T32AG058503-04). J.S.H. acknowledges funding support from the NUS iHealthtech Institute.
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S.A.K., K.A.K., Q.X., X.T., P.G. and J.S.H. conceived and planned the research. S.A.K. and X.T. designed the dual-mode metamaterial textile. K.A.K., S.A.K. and P.G. designed and fabricated the battery-free epidermal sensors and dry electrodes. S.A.K. and Q.X. performed the electromagnetic simulations and characterized the wireless system. S.A.K., K.A.K. and Q.X. conducted the benchtop characterization and signal monitoring experiments. X.Y., X.X., Q.Z., T.S., Z.L., Y.L., J.S. and W.D. contributed to the experimental setup and study design. S.A.K., K.A.K., Q.X., X.T., P.G. and J.S.H. wrote the paper with input from all authors. X.T., P.G. and J.S.H. supervised the entire project.
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Kurt, S.A., Kasper, K.A., Xu, Q. et al. A battery-free wireless epidermal sensor network for continuous systolic blood pressure monitoring. Nat Electron (2026). https://doi.org/10.1038/s41928-026-01597-1
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DOI: https://doi.org/10.1038/s41928-026-01597-1