Fig. 1: The protective effect of riboflavin on ALD in mice.
From: Intestinal microbiota homeostasis analysis in riboflavin-treated alcoholic liver disease
a A flowchart showed the whole process of mouse treatment. b The representative diagram of liver tissues shown that alcohol induced steatosis changes, and riboflavin alleviate the effect of alcohol diet. The black arrow in the figure was to show the steatosis changes part of the liver. c The rate of liver weight to the body weight result shown that alcohol increased the rate of mouse liver weight to the body weight, which was decreased by riboflavin. d HE staining representative images (400×) shown the hepatic steatosis and inflammatory cell infiltration of the alcohol groups mouse livers, which was alleviated by riboflavin. e ALT level was upregulated in the alcohol induced mouse liver tissues, which was alleviated by riboflavin. f AST level was upregulated in the alcohol induced mouse liver tissues, which was alleviated by riboflavin. g TG level was upregulated in the alcohol induced mouse liver tissues, which was alleviated by riboflavin. h TC level was upregulated in the alcohol induced mouse liver tissues, which was alleviated by riboflavin. *P < 0.05, **P < 0.01, ***P < 0.001vs. Control; #P < 0.05, ###P < 0.001 vs. Alcohol. n = 5. Data were presented as mean ± standard error of mean (SEM). AR alcohol + riboflavin, ALD alcoholic liver disease.
