Fig. 4: MAZ regulates cell cycle to promote melanoma cell proliferation. | Communications Biology

Fig. 4: MAZ regulates cell cycle to promote melanoma cell proliferation.

From: Molecular mechanisms of MAZ targeting up-regulation of NDUFS3 expression to promote malignant progression in melanoma

Fig. 4

a GSEA analyses MAZ in relation to the cell cycle. b Flow cytometry analysis of the effect of MAZ on melanoma cell cycle phase distribution. c Correlation of MAZ with cell cycle regulators analyzed by GEO and TCGA databases. d Western Blot detection of cell cycle regulatory factors in MAZ overexpression/knockdown cells at protein levels. The experimental data were normalized. Student’s t-test was used to analyse the experimental results of the MAZ-OE and MAZ-KD groups with their control groups. (mean ± SEM, n = 3). (***p < 2e-4, **p < 2e-3, *p < 0.05).

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