Fig. 7: Bioinformatic analysis of PLAC8-interacting proteins in A549 cells. | Communications Biology

Fig. 7: Bioinformatic analysis of PLAC8-interacting proteins in A549 cells.

From: PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy

Fig. 7

a Schematic diagram of the COIP/MS analysis of PLAC8-interacting proteins in A549 cells. b Percentages of specific PLAC8-interacting proteins in A549 cells. c KEGG enrichment analysis of PLAC8-interacting proteins. d The proteins enriched in Lysosome, Apoptosis, and Autophagy pathways in KGEE from (c). e GO enrichment analysis of PLAC8-interacting proteins. f The proteins enriched in Autophagy, autophagosome maturation, lysosome organization, and proteasome-mediated ubiquitin-dependent protein catabolic process pathways in GO analysis of BP from (e). g The proteins enriched in p53 binding, DNA-binding transcription factor binding, Ubiquitination-like modification-dependent protein binding, and Ubiquitination-dependent-protein binding in GO analysis of MF from (e). h Protein-protein interaction (PPI) network analysis of protein from (g) from the STRING database (https://cn.string-db.org/).

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