Fig. 2: Development and validation of a 12-gene fitness RSF model. | Communications Biology

Fig. 2: Development and validation of a 12-gene fitness RSF model.

From: Selective inhibition of TGF-β-induced epithelial-mesenchymal transition overcomes chemotherapy resistance in high-risk lung squamous cell carcinoma

Fig. 2: Development and validation of a 12-gene fitness RSF model.

A Core fitness gene selection in LUSC. B The 5-year AUCs and C-indices for seven prognostic models in the overall TCGA-LUSC dataset (n = 493). C Kaplan-Meier estimates of overall survival according to the RSF risk score in the training cohort from TCGA (n = 345) (Log-rank test). D Kaplan-Meier estimates of overall survival according to the RSF risk score in the test cohort from TCGA (n = 148) (Log-rank test). E Kaplan-Meier estimates of overall survival according to the RSF risk score in the GSE157011 cohort (n = 484) (Log-rank test). F Multivariate Cox regression analysis of the RSF and seven prognostic models in the overall TCGA-LUSC dataset (n = 493). G Multivariate Cox regression analysis of the RSF and seven prognostic models in the GSE157011 cohort (n = 484).

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