Fig. 5: Associations of genetically proxied ACLY inhibitor with the levels of melanoma-associated proteins. | Communications Biology

Fig. 5: Associations of genetically proxied ACLY inhibitor with the levels of melanoma-associated proteins.

From: Genetic insights support PARP1 as a mediator in the protective association of ATP-citrate lyase inhibitors with melanoma

Fig. 5

The effects of genetically proxied ACLY inhibitors on 3 melanoma-associated proteins were represented as Beta [95% CI] per 1-SD decrease in blood ACLY expression. POGLUT3 protein O-glucosyltransferase 3, MAP1LC3A microtubule-associated protein 1 light chain 3 alpha, PARP1 poly [ADP-ribose] polymerase 1.

Back to article page