Fig. 1: Manhattan plot representations of the three trans-ethnic meta-analyses conducted between the two European and the Asian genome-wide association studies of male infertility due to spermatogenic failure (SPGF). | Communications Biology

Fig. 1: Manhattan plot representations of the three trans-ethnic meta-analyses conducted between the two European and the Asian genome-wide association studies of male infertility due to spermatogenic failure (SPGF).

From: Trans-ethnic GWAS meta-analysis of idiopathic spermatogenic failure highlights the immune-mediated nature of Sertoli cell-only syndrome

Fig. 1

The inverse variance meta-analysis was performed by combining the results of the “NOA vs controls” comparison from Asians with those of the “SPGF vs controls” (A), “non-obstructive azoospermia (NOA) vs controls” (B), and “Sertoli cell-only syndrome (SCO) vs controls” (C) comparisons from Europeans. The red line represents the genome-wide level of significance (P-value < 5E−08).

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