Fig. 3: Results of graph theoretical analysis. | Communications Biology

Fig. 3: Results of graph theoretical analysis.

From: White matter dysfunction in Alzheimer’s disease is associated with disease-related transcriptomic signatures

Fig. 3: Results of graph theoretical analysis.The alternative text for this image may have been generated using AI.

a, b The ROI distribution of WM and GM, respectively. c Group differences in the global topological properties of WM, GM, and whole-brain functional networks. Box plots show the area under the curve (AUC) value of the topological metric for each group. Boxes denote the 25th to 75th centiles and the median line. The whiskers extend from the 5th to the 95th centiles, and data points beyond the whiskers are displayed as outliers. An asterisk indicates significant differences. The nodal topological properties differences in WM (d) and GM (e) among AD, MCI, and CU (left column), between AD and CU (second column), between MCI and CU (third column), and between AD and MCI (right column). Region colors indicate the positive (red) or negative (blue) statistical value. FDR correction was used for multiple comparisons with P < 0.05. GM gray matter, WM white matter, AD Alzheimer’s disease, MCI mild cognitive impairment, CU cognitively unimpaired.

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