Fig. 2: Summary of protein interaction prediction process. | Communications Biology

Fig. 2: Summary of protein interaction prediction process.

From: Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway

Fig. 2: Summary of protein interaction prediction process.

A Total motifs in the initial search depending on motif type (R-F-x-V/I or R-x-F-x-V/I). B Multiple sequence alignment of all experimentally identified motifs identified from the literature5,7,8,9,10,11,12,13,16,19,33,34,44,63,76,77,78,79,80,81,82. Literature references for each motif are in the Supp. Fig. 4A. Alignments generated with Clustal Omega (clustal.org). Sequence logo generated with WebLogo (weblogo.berkeley.edu). C Flowcharts for process predicting CCT interactions and with scoring information in Supp. Fig. 4B.

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