Fig. 2: The enrichment profile of transcription factors within regulatory T cells (Tregs) derived from blood and tissue. | Communications Biology

Fig. 2: The enrichment profile of transcription factors within regulatory T cells (Tregs) derived from blood and tissue.

From: Targeting VCAM-1 with chimeric antigen receptor and regulatory T cell for abdominal aortic aneurysm treatment

Fig. 2

The heatmap of transcription factor enrichment in Tregs from AAA patients (A), the corresponding heatmap in normal controls (B), upregulated transcription factor FOXP3 extended in AAA, including AUC scores and gene set activity with enriched Ridgeplot (C), significant differences in antigen presentation-related STAT1 between AAA and normal groups, with detailed AUC scores and gene set activity visualized by Ridgeplot (D), IRF1 upregulated in AAA, including AUC scores and gene set activity with enriched Ridgeplot (E), and upregulated transcription factor EZH2 in AAA, including AUC scores and gene set activity with enriched Ridgeplot (F).

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