Fig. 5: Kv11.1 reduces the steady-state levels of the c-Myc protein and increases expression of genes repressed by c-Myc. | Communications Biology

Fig. 5: Kv11.1 reduces the steady-state levels of the c-Myc protein and increases expression of genes repressed by c-Myc.

From: Activation of Kv11.1 potassium channel suppresses non-small cell lung cancer growth by promoting c-Myc degradation

Fig. 5

A Western blot showing the effect of NS1643 treatment (50 mM; 0-30-60-120 min) on c-Myc protein level in A549, H1299 or B H1437, H1650 lung cancer cell lines. Bar graph showing quantification of the events in (A, B). C Bar graph shows mRNA expression for FASN, DUSP1, and GaDD45A in A549 or D H1299 lung cancer cell lines after 24 h NS1643 treatment.

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