Fig. 2: Deregulated genes of the transforming growth factor-β pathway.

The heatmaps depict significantly (p < 0.05) differentially expressed transforming growth factor-β (TGFβ) genes with the gene ontology terms GO:0030511, 0030512, and 0071560 of ASCsub35 vs. ASCsub 25 (A) and of ASCsub40 vs. ASCsub 25 (B). Significantly enriched genes have a red color code and reduced genes are encoded in blue. Red and blue colored genes are sorted alphabetically. C–F Truncated violin plots present selected genes that are expressed differentially. Values reflect the fragments per kilobase per million mapped fragments (fpkm) of genes from the RNA‑seq data. Each violin plot displays the median (central dashed line) and quartiles (upper and lower dotted lines).