Fig. 5: CNA signature comparison between single-cell and bulk tissue samples. | Communications Biology

Fig. 5: CNA signature comparison between single-cell and bulk tissue samples.

From: Single-cell copy number alteration signature analysis reveals masked patterns and potential biomarkers for cancer

Fig. 5

A Bulk tissue sample generated from corresponding single cells, and the distribution of scSig as a percentage of the total is presented. B The mean proportion of each scSig across all cells within each sample is calculated, showing the average distribution of scSig within each sample. C At the bulk tissue level, the distribution of scSig in sample P04 and scSig4 accounts for 96.7%. D At the single-cell level, the distribution of scSig in sample P04 and scSig3 accounts for a relatively large proportion. Various scSig are present.

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