Fig. 7: Synergistic role of cueO and copA in capsular polysaccharide and biofilm production in K. pneumoniae.
From: A critical role of copper homeostasis in the virulence of Klebsiella pneumoniae
a String test assessing capsule formation. n = 3 biological replicates. Unpaired t-test. b qRT-PCR measurement of transcript levels for capsule biosynthesis genes (rmpA, rmpC, and wcaG) in K. pneumoniae. n = 3 biological replicates. Unpaired t-test. c Biofilm formation was quantified by measuring the absorbance at 595 nm. n = 3 biological replicates. Unpaired t-test. d Transmission electron microscopy (TEM) images (4000× magnification) illustrating differences between wild-type and mutant strains; scale bar = 500 nm. Data are represented as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns indicates not significant.
