Fig. 2: Quantification of RhCMV DNA at the maternal-fetal (M-F) interface. | Communications Biology

Fig. 2: Quantification of RhCMV DNA at the maternal-fetal (M-F) interface.

From: A rhesus macaque model of congenital cytomegalovirus infection reveals a spectrum of vertical transmission outcomes

Fig. 2: Quantification of RhCMV DNA at the maternal-fetal (M-F) interface.

A RhCMV DNA detection in amniotic fluid (AF) of five AF+ dams. Viral loads expressed as mean RhCMV DNA copies per mL of AF. Data on mean of 12 PCR replicates per time-point. B Schematic diagram of rhesus macaque M-F interface tissues. Created in BioRender. Manuel, T. (2025) (https://BioRender.com/501tyz9). C Heatmap illustrating mean RhCMV DNA copies per µg of input DNA within tissues of the M-F interface of each dam within AF+ and AF– group. Mean copy number of 12 PCR replicates shown. Gray boxes (ND) indicate no sample collected. White boxes (0) indicate no viral DNA was detected in the sample. D Heatmap showing number of RhCMV-positive cells per cm2 by in situ hybridization (ISH) in full-thickness placental cross-sections of individual AF+ and AF– dams.

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