Fig. 1: SARS-CoV-2-specific binding and neutralizing antibody levels in Group S and M. | Communications Biology

Fig. 1: SARS-CoV-2-specific binding and neutralizing antibody levels in Group S and M.

From: Anti-SARS-CoV-2 antibodies from severe COVID-19 individuals or S2 immunizations do not worsen disease in hamsters

Fig. 1

Comparison of IgG, IgA, and IgM binding antibody levels (from left to right) in unvaccinated individuals with severe (Group S, blue squares) and mild COVID-19 (Group M, red circles) targeting (A) S2, (B) RBD, (C) Nucleocapsid, and (D) Envelope. Binding antibody levels in plasma samples are expressed as arbitrary units/ml. E Plasma neutralizing activity was evaluated against SARS-CoV-2 WH-1. Differences between both groups were analyzed using Peto&Peto censored samples test. Geometric mean with its geometric standard deviation is shown. The number of individuals with detectable antibodies out of the group total is indicated below each group. Dotted lines indicate the upper and lower limit of quantification. Undetectable samples are represented as half this threshold, and samples above the upper limit are represented as twice this threshold.

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