Table 1 Patient demographics and clinical characteristics

From: Anti-SARS-CoV-2 antibodies from severe COVID-19 individuals or S2 immunizations do not worsen disease in hamsters

Group

Severe (n = 74)

Mild (n = 25)

Age - mean (range)

54 (29–80)

47 (25–92)

Male sex - n° (%)

55 (74.3%)

11 (44%)

COVID-19 vaccination - n° (%)

0 (0%)

0 (0%)

Diagnosis test

 PCR

60 (81.1%)

21 (84%)

 Antigen test

14 (18.9%)

3 (12%)

 Serology

0

1(4%)

Sample collection POS - days (%)

 0–14

33 (44.6%)

17 (68%)

 15–31

41 (55.4%)

7 (28%)

 Risk factors for severe Covid-19 - n° (%)

47 (64%)

14 (56%)

 Individuals with more than 1 risk factor

26 (35.1%)

7 (28%)

 Obesity

22 (29.7%)

4 (16%)

 Diabetes

18 (24.3%)

3 (12%)

 Hypertension

22 (29.7%)

6 (24%)

 Rheumatoid arthritis

1 (1.4%)

1 (4%)

 Chronic liver disease

6 (8.1%)

3 (12%)

 Chronic kidney disease

4 (5.4%)

2 (8%)

 Heart disease

1 (1.4%)

4 (16%)

 Pneumopathy

9 (12.2%)

4 (16%)

 Pregnancy

0 (0%)

6 (24%)

 Smoking

2 (2.7%)

0 (0%)

Antiviral therapies/treatment

 >1 treatment/patient

51 (69%)

3 (12%)

 Corticosteroids

48 (64.9%)

7 (28%)

 Antivirala

49 (66.2%)

6 (24%)

 Antibodiesb

28 (37.8%)

1 (4%)

 Other

4 (5.4%)

1 (4%)

  1. ai.e., Remdesivir, lopinavir, Ritonavir, Darunavir, Cobicistat, Oseltamivir.
  2. bi.e., Tocilizumab, Siltuximab.