Fig. 2: Visualisation of four illustrative substrates used for MC diffusion simulations. | Communications Biology

Fig. 2: Visualisation of four illustrative substrates used for MC diffusion simulations.

From: Histology-informed microstructural diffusion simulations for MRI cancer characterisation—the Histo-μSim framework

Fig. 2

a, d, g, j HE histological images. b, e, h, k SVG files reconstructed with the Blender software package, showing different substrate features (e.g., cells and debris in green, vessels in red, lumina in dark blue). c, f, i, l Histograms depicting the CS (i.e., cell diameter) distribution for each substrate, with summary statistics and with a Gamma distribution fit superimposed onto it (black solid line). From top to bottom: non-cancerous liver (substrate 4), colorectal cancer (substrate 8), breast cancer (substrate 17), melanoma (substrate 18).

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