Table 3 Mean values of metrics from the analytical signal model and from histology within different ROIs drawn on the breast, kidney, and spleen tissue scanned ex vivo on a pre-clinical 9.4T MRI system
Description | fin∣histo | fin∣AN | vCSsph∣histo | vCScyl∣histo | mCShisto | vCSsph∣AN |
|---|---|---|---|---|---|---|
[μm] | [μm] | [μm] | [μm] | |||
ROI 1: Breast tumour - Week 9 (cellular area) | 0.70 | 0.76 | 8.6 | 8.4 | 7.5 | 16.9 |
ROI 2: Breast tumour - Week 14 (necrosis) | 0.03 | 0.17 | 4.5 | 4.4 | 4.0 | 15.6 |
ROI 3: Breast tumour - Week 14 (cellular area) | 0.72 | 0.65 | 10.4 | 10.1 | 9.0 | 16.5 |
ROI 4: Breast tumour - Week 11 (cellular area) | 0.64 | 0.64 | 8.7 | 8.4 | 7.2 | 14.3 |
ROI 5: Non-cancerous breast | 0.11 | 0.06 | 7.7 | 7.4 | 6.3 | 13.9 |
ROI 6: Breast tumour - Week 9 (cellular area) | 0.68 | 0.61 | 5.7 | 5.6 | 5.2 | 8.4 |
ROI 7: Breast tumour - Week 9 (cellular area) | 0.55 | 0.80 | 8.0 | 7.7 | 6.8 | 13.1 |
ROI 8: Breast tumour - Week 9 (cellular area) | 0.76 | 0.69 | 8.8 | 8.6 | 7.6 | 13.5 |
ROI 9: Breast tumour - Week 11 (cellular area) | 0.81 | 0.80 | 9.6 | 9.4 | 8.7 | 17.0 |
ROI 10: Breast tumour - Week 11 (cellular area) | 0.84 | 0.59 | 11.0 | 10.8 | 9.9 | 15.3 |
ROI 11: Breast tumour - Week 11 (cellular area) | 0.77 | 0.57 | 9.1 | 8.9 | 8.1 | 15.0 |
ROI 12: Breast tumour - Week 14 (necrosis) | 0.01 | 0.06 | 2.0 | 1.9 | 1.7 | 15.1 |
ROI 13: Breast tumour - Week 14 (cellular area) | 0.74 | 0.63 | 9.7 | 9.5 | 8.5 | 15.8 |
ROI 14: Breast tumour - Week 14 (cellular area) | 0.77 | 0.55 | 9.8 | 9.5 | 8.8 | 14.4 |
ROI 15: Injured kidney | 0.66 | 0.63 | 6.0 | 5.8 | 5.0 | 17.0 |
ROI 16: Healthy kidney | 0.82 | 0.05 | 11.8 | 11.6 | 10.1 | 15.0 |
ROI 17: Healthy spleen | 0.75 | 0.39 | 5.2 | 5.1 | 4.4 | 10.7 |
ROI 18: Splenomegaly | 0.64 | 0.32 | 4.7 | 4.6 | 4.0 | 11.2 |
