Table 5 dMRI and histology metrics in cancer patients, with salient patients’ demographic and clinical information

From: Histology-informed microstructural diffusion simulations for MRI cancer characterisation—the Histo-μSim framework

Patient information / MRI scanner

Primary cancer

fin∣histo

fin∣AN

vCSsph∣histo [μm]

vCScyl∣histo [μm]

mCShisto [μm]

vCSsph∣AN [μm]

    

[μm]

[μm]

[μm]

[μm]

Case 0, 75-80 y.o., F, 3T scanner

colon

0.58

0.25

14.5

13.8

11.4

11.7

Case 1, 60-65 y.o., M, 3T scanner

colon

0.33

0.18

16.1

15.4

11.9

11.6

Case 2, 60-65 y.o., M, 3T scanner

renal

0.29

0.34

13.7

13.1

9.7

11.7

Case 3, 65-70 y.o., M, 3T scanner

colon

0.23

0.21

14.6

14.0

10.9

11.4

Case 4, 65-70 y.o., M, 3T scanner

colon

0.56

0.20

14.2

13.6

11.2

11.4

Case 5, 70-75 y.o., M, 3T scanner

colon

0.57

0.21

14.6

14.0

11.6

11.7

Case 6, 65-70 y.o., M, 3T scanner

colon

0.47

0.20

15.1

14.4

11.5

11.2

Case 7, 45-50 y.o., F, 3T scanner

melanoma

0.64

0.20

16.3

15.6

13.0

11.4

Case 8, 75-80 y.o., F, 3T scanner

rectal

0.57

0.12

14.1

13.6

11.4

11.5

Case 9, 50-55 y.o., M, 3T scanner

HCC

0.002

0.18

7.4

7.2

6.6

11.5

Case 10, 60-65 y.o., F, 3T scanner

ovarian

0.52

0.19

16.8

16.1

13.7

11.6

Case 11, 55-60 y.o., M, 3T scanner

rectal

0.68

0.17

14.7

14.1

11.9

11.7

Case 12, 35-40 y.o., F, 3T scanner

breast

0.34

0.25

16.1

15.5

13.3

11.4

Case 13, 80-85 y.o., F, 3T scanner

endometrial

0.46

0.29

14.5

13.6

9.9

11.4

Case 14, 55-60 y.o., F, 3T scanner

melanoma

0.75

0.24

15.1

14.5

12.4

11.4

Case 15, 55-60 y.o., M, 3T scanner

pancreatic

0.83

0.20

14.5

13.9

12.0

11.4

Case 16, 55-60 y.o., F, 3T scanner

breast

0.78

0.12

12.6

12.2

10.6

11.5

Case 17, 60-65 y.o., F, 1.5T scanner

endometrial

0.41

0.31

13.0

12.3

9.9

11.7

Case 18, 60-65 y.o., M, 1.5T scanner

esophagus

0.003

0.05

7.6

7.4

6.7

11.8

Case 19, 60-65 y.o., F, 1.5T scanner

melanoma

0.77

0.34

14.3

13.9

12.4

12.4

Case 20, 50-55 y.o., F, 1.5T scanner

ovarian

0.79

0.23

14.2

13.6

11.9

11.8

Case 21, 65-70 y.o., M, 1.5T scanner

melanoma

0.71

0.37

15.3

14.9

13.2

12.3

Case 22, 75-80 y.o., M, 1.5T scanner

melanoma

0.70

0.25

15.4

14.9

13.0

11.4

Case 23, 65-70 y.o., M, 1.5T scanner

HCC

0.40

0.25

15.5

14.9

12.3

12.2

Case 24, 65-70 y.o., F, 1.5T scanner

gastric

0.31

0.21

14.3

13.6

10.7

12.0

Case 25, 60-65 y.o., F, 1.5T scanner

melanoma

0.55

0.24

15.8

15.3

13.2

11.8

Case 26, 30-35 y.o., F, 1.5T scanner

breast

0.73

0.25

14.2

13.7

12.0

10.9

  1. dMRI metrics are derived from the standard analytical signal model
  2. The table reports dMRI metrics from fitting of an analytical, multi-compartment signal model of hindered EC diffusion and restricted IC diffusion within spherical, impermeable cells. Patients’ age has been discretised with a granularity of 5-year intervals. HCC stands for hepatocellular carcinoma (primary liver cancer).
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