Fig. 1: Schematic overview of the Pioneer 100 Horse Health Cohort.
From: Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses

Animals were actively selected into the cohort from the resident population of horses at the UC Davis Center for Equine Health. Animals were required to meet age, breed, and sex ratio selection prior to entry into the study. The minimum amount of data collection for animals included in the study requires a high coverage whole-genome sequence (WGS) and an accessible medical record. Animals underwent extensive prospective phenotyping by body system and sample collection for biorepository creation. Disease phenotypes that occur spontaneously or were known at entry in the study are also documented. Created in BioRender. Donnelly, C. (2025) https://BioRender.com/s82ldgd.