Fig. 4: Metabolic and microbiota interaction in horses with MetS.
From: Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses
A Box and Whisker plot of runs of homozygosity (ROH). Horses from the thoroughbred breed group had the highest across-genome ROH (mean ± SD; 148,464 ± 24,497 bp). The other two major groups, Quarter Horse (81,141 ± 11,509 bp) and Warmblood (85,629 ± 15,418 bp), had approximately half the ROH length as Thoroughbreds. The small number of Thoroughbred x Quarter Horse crossed horses demonstrated an intermediary ROH. B Heatmap of Pearson correlation coefficients for ROH, insulin and BCS/ All correlations were significant (P < 0.0001). QH quarter horse, WBxQH warmblood cross quarter horse, TB thoroughbred, TBxQH thoroughbred cross quarter horse, WB warmblood, ROH runs of homozygosity, bp base pairs, BCS body condition score.
