Fig. 4: TCI in organ transplantation recipients.
From: Tracing the tissue origin of cell-free DNA through open chromatin footprint
a The average Base Counts Per Million mapped bases (BCPM) profiles at single base pair resolution across 1000 bp upstream and downstream of transcriptional start site (TSS) of liver tissue-specific highly expressed genes (SH-genes) in liver transplant recipients grouped by donor cfDNA fraction. b Correlation between liver Tissue Contribution Index (TCI) and donor cfDNA fraction in 12 liver transplant recipients. c The average BCPM at single base pair resolution across 1000 bp upstream and downstream of TSS of blood cell SH-genes in bone marrow transplant recipients grouped by donor cfDNA fraction. d Correlation between blood cell TCI and donor cfDNA fraction in bone marrow transplant recipients. The shaded area in (a–d) represents the 95% confidence interval.
