Fig. 1: Comparative analysis of m6A modification detection by scDART-seq, scm6A-seq, sn-m6A-CT, and Scm6A at the single-cell level.
From: Systematic evaluation of tools used for single-cell m6A identification
A The bar chart visually represents the proportion of miCLIP-validated m6A-modified genes among those identified by each method. Blue indicates m6A sites detected by the method that match miCLIP sequencing results, while yellow indicates those that do not match. B The distribution patterns of m6A sites detected by each method across different regions of the mRNA transcript, including the 5’ UTR, CDS, and 3’ UTR. C Sequence motif analysis of m6A sites identified by the four methods and two miCLIP reference datasets, demonstrating the preference of different detection methods for specific motif sequences.
