Fig. 3: Spatial analysis of m6A modifications in UCEC tissues using Scm6A and spatial transcriptomics.
From: Systematic evaluation of tools used for single-cell m6A identification
A, B UMAP and spatial transcriptomic maps generated using the expression profiles of all genes in the sample. These maps show the clustering of cells based on their gene expression patterns, with each cluster represented by different colors corresponding to distinct cell identities or states. C, D UMAP and spatial transcriptomic maps highlighting the expression of RBP genes within the sample. The clustering patterns emphasize the distribution and localization of RBP expression across the tissue. E, F UMAP and spatial transcriptomic maps based on m6A modifications predicted using the Scm6A software. These maps display the distribution of single-cell m6A methylation across different regions of the tissue, illustrating the spatial heterogeneity of m6A modifications.
