Fig. 6: miR-299a-5p inhibition reduces fibrosis in DKD. | Communications Biology

Fig. 6: miR-299a-5p inhibition reduces fibrosis in DKD.

From: miR-299a-5p is a mediator of fibrosis in diabetic kidney disease by regulating follistatin and cripto-1

Fig. 6

A–E Increased fibrosis was seen in DKD, assessed by PSR (A, B) and IHC for fibronectin, collagen IVα1 and CTGF (C–E). All were reduced by miR-299a-5p inhibition. F–I Immunoblotting for fibronectin, collagen 1α1 and CTGF showed similar results (*p < 0.05, **p < 0.01, ****p < 0.0001). Data presented as mean ± SEM. The scale bar represents 100 µm.

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