Table 2 Non-synonymous mutations identified in the four key insecticide resistance genes

From: Genome-wide analysis of genetic diversity in Anopheles darlingi from Rondônia State, Brazil

Gene

Chr

Position

Ref

Alt

Codon Change in An. darlingi

Codon in An. gambiae PEST

Codon in Musca domestica

Alternate Allele Frequency %

        

Wild-caught (n = 20)

Colony (n = 8)

ace1

2

15676267

T

C

Val32Alaa

Ala27b

-

56.7

50.0

gste2

2

89825712

A

G

Asn82Serc

Asp82d

Asp82i

2.94

0

gste2

2

89825747

G

A

Ala94Thrc

Ala94d

Ala94i

13.3

0

gste2

2

89825962

G

A

Glu142Lysc

Glu142d

Glu142i

2.94

0

gste2

2

89827309

G

C

Val276Leuc

Val57d

Thr57i

83.3

50.0

vgsc

3

35318429

C

T

Pro523Leue

Pro509f

Pro529 j

2.94

0

rdl

3

53427108

G

A

Ser90Asng

Ser90h

Ser93k

3.33

0

  1. An. darlingi colony (n = 8) and wild (n = 20) mosquitoes.
  2. aCodon numbering according to Anopheles darlingi transcript XM_049679441.
  3. bCodon numbering according to Anopheles gambiae transcript XM_061649305.
  4. cCodon numbering according to Anopheles darlingi transcript XM_049692446.
  5. dCodon numbering according to Anopheles gambiaetranscript AGAP009194-PA.
  6. eCodon numbering according to Anopheles darlingi transcript XM_049687134.
  7. fCodon numbering according to Anopheles gambiae transcript AGAP004707-PB.
  8. gCodon numbering according to Anopheles darlingi transcript XM_049684483.
  9. hCodon numbering according to Anopheles gambiae transcript AGAP006028-PB.
  10. ICodon numbering according to Musca domestica transcript XP_058986999.
  11. jCodon numbering according to Musca domestica transcript ARX79626.
  12. kCodon numbering according to Musca domestica transcript NP_001292048.1.
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