Fig. 8: Comparisons between AC, mPFC, and hippocampal responses. | Communications Biology

Fig. 8: Comparisons between AC, mPFC, and hippocampal responses.

From: Neuronal mismatch responses to auditory stimuli in the dorsal hippocampus of anesthetized rats

Fig. 8

A Average responses for the first 10 STD trials (mean ± SEM) in the lemniscal AC (L-AC, green, dotted line), nonlemniscal AC (nL-AC, orange, dotted line), mPFC (gray, dotted line), DG (red, solid trace), and CA1 (blue, solid trace). Error bars indicate ± SEM. Open circles indicate the trial at which the STD falls below 50% relative to the first trial. Arrowheads on the left represent the minimum response to STD during the sequence, as determined by the steady-state (SS) parameter of a three-parameter power-law fit for AC and PFC, while for CA1 (n = 21; 6 rats) and DG (n = 22; 5 rats), it shows the lowest STD response observed across all trials. B Median iPE (orange) and iRS (cyan) values for each AC, PFC or hippocampus subdivision recorded, referenced against the baseline set by the CTR. Here, iPE is plotted as positive in the upward direction, while iRS is plotted as positive in the downward direction (see Fig. 1D). AC and PFC data originates from Parras et al. (2017) and Casado-Román et al. (2020), respectively. Asterisks indicate statistical significance of each index compared to a zero median (n.s., nonsignificant; *p < 0.05; **p < 0.01; ***p < 0.001; t-test with Holm-Bonferroni correction). The underlying data for this Figure can be found in Supplementary Data 4.

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