Fig. 1: UV induced mutations in epidermis.
From: The dynamics of mutational selection in cutaneous squamous carcinogenesis
a Protocol. Following sub-minimal erythema UV dose epidermis and tumors are dissected and sequenced as shown. b, c Mutational burden in irradiated dorsal epidermis. b Substitutions/Megabase, c double base substitutions/megabase, both determined by NanoSeq. Each dot represents one mouse, red bar indicates the median. Source Data: Supplementary Data 3d Density of mutations, each dot is a different epidermal grid sample, grouped by mouse. Source data: Supplementary Data 3, 5.
