Fig. 5: Predicted 2:2 complex model of AcrIIA19 and Cas9.
From: AcrIIA19 binds to the WED domain and inhibits various Cas9 orthologs at multiple stages
A Complex structural model generated by AF3. B The raw profile of SEC-MALS. Assays are represented as black bars. UV and LS indicate ultraviolet and light scattering, respectively. C Profiles of MALS analysis (1st, 2nd, and 3rd peaks). The experimental MALS data (red line) plotted on the SEC chromatogram (black) with the x-axis representing the SEC elution volume and y-axis representing the absolute molecular mass.
