Fig. 7: Analysis by SAXS of complexes FXN:NB_28F6 and FXN:NB_16C10.
From: Nanobodies as tools for studying human frataxin biology
A, B Fit of the experimental scattering curve (green and pink dots) and theoretical scattering (green and pink lines) computed for the model of FXN:NB_28F6 and FXN:NB_16C10. C Plot showing the normalized pair-distance distribution function P(r) for the complexes reflecting the distance distribution. D The upper figure represents the superimposition on the ab initio-determined SAXS envelope (pale gray) for FXN:NB_28F6 complex with the AlphaFold3 predicted model. The bottom figure represents the superimposition on the ab initio-determined SAXS envelope (pale gray) for FXN:NB_16C10 with its crystal structure-based model.
