Fig. 3: Generation of the vascular organoids derived from HC individuals and MMD patients.
From: Organoid Modeling and Single-Cell Profiling Reveal Smooth Muscle Cell Migration in Moyamoya Disease
A The flowchart of vascular organoid generation derived from HC and MMD patients. B Bright-field images of human induced pluripotent stem cells (iPSCs) differentiation into vascular organoids (day-3 – day25). Scale = 300 μm. MMD Moyamoya Disease, HC Healthy Controls. C Representative immunofluorescence of CD31 and αSMA expressing endothelial and smooth muscle cells, respectively, shows the establishment of vascular networks. CD31, red; αSMA, green; DAPI, blue; HC Healthy Controls; MMD, Moyamoya Disease. Scale 100 μm.
