Fig. 6: The adaptive evolution in giant panda genome exerts its function in a tissue-specific manner.
From: A compendium of chromatin interaction maps in the Giant Panda genome
a The enrichment score of the selective signatures of Qinling population in the tissue-specific enhancers relative to the stable enhancers (fold changes are shown). b Selective signatures enrichment in tissue-specific enhancers among Qinling, Qionglai and Minshan populations. Example of selective signatures in the Minshan population located within a small intestine-specific enhancer (c) and a subcutaneous adipose-specific enhancer (d), respectively. The Hi-C maps around the tissue-specific enhancers and their interacting promoters in the nine giant panda tissues were shown. Genome browser tracks show the the FST and θπ ratios between Qinling and Minshan (black bordered, θπ ratio: θπ, Qinling/θπ, Minshan) and between Qionglai and Minshan (without border, θπ ratio: θπ, Qionglai/θπ, Minshan). The target PCGs are marked in red. The dashed line boxes indicate the chromosomal locations of the tissue-specific enhancer and its interacted promoter. E: enhancer, P: Promoter.
