Fig. 3: Cross-species comparisons reveal convergent desert-adaptive evolution of lipid/sterol metabolism. | Communications Biology

Fig. 3: Cross-species comparisons reveal convergent desert-adaptive evolution of lipid/sterol metabolism.

From: INSIG1 parallel substitution drives lipid/sterol metabolic plasticity mediating desert adaptation in ungulates

Fig. 3: Cross-species comparisons reveal convergent desert-adaptive evolution of lipid/sterol metabolism.The alternative text for this image may have been generated using AI.

A The number of conservative parallel amino acid substitutions sites (red) and genes (blue) detected in 25 pairwise comparisons among Camelus and Hippotraginae lineages. B Functional GO terms enriched by parallel amino acid substitution genes. C Bar chart showing the percentage of super-class for identified metabolites in fatty acids, sterol lipids, and other metabolites of fasting camel and fasting mouse. Heatmap further showing the differences in identified fatty acid and sterol lipid metabolites super-class between camel and mouse. Red: sterol lipids; Green: fatty acid. n = 4 samples for male mice and camel. Animal silhouettes in (C) were obtained from PhyloPic (http://phylopic.org), which provides free silhouette images of organisms. The silhouettes used here are available for reuse under the Creative Commons Attribution 4.0 International License (CC BY 4.0; https://creativecommons.org/licenses/by/4.0/).

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