Fig. 3: Silencing PiR48444 promotes the repair of calvarial defects with cell sheets. | Communications Biology

Fig. 3: Silencing PiR48444 promotes the repair of calvarial defects with cell sheets.

From: PiR48444 inhibits MSC osteogenic differentiation and bone regeneration via targeting METTL7A/eIF4E-mediated BMP2 m6A methylation

Fig. 3: Silencing PiR48444 promotes the repair of calvarial defects with cell sheets.

A Representative MicroCT images. B MicroCT images in vertical view. C Bone volume/total volume (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp) (n = 6). D H&E staining. E Masson staining. Data in (C) are presented as mean ± SD; statistical analysis via Student’s t test for two-group comparisons. Significance levels: **p < 0.01. NB new bone.

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