Fig. 1 | Communications Chemistry

Fig. 1

From: Lewis base-catalyzed intermolecular triazene alkyne cycloaddition for late-stage functionalization and scaffold diversification

Fig. 1

Recent directions and envisaged approach for 3-trifluoromethylpyrazoles synthesis. a Importance of 3-trifluoromethylpyrazoles. b Known protocols of 3-trifluoromethylpyrazoles synthesis and limitations. c Proposed triazene-alkyne cycloaddition for the direct [3 + 2] assembly of 3-trifluoromethylpyrazoles, late-stage functionalization, and scaffolds diversification

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