Fig. 6

Frequency of robust HBs in protein-fragment complexes. a Histogram of frequency of HBs by WQB value for all simulated HBs (124) in SERAPhiC dataset. b Pie chart showing share of complexes with at least one robust HB (WQB > 6 kcal mol−1, pink), all labile HBs (WQB < 4 kcal mol−1, green) or intermediate situations (red) for all protein-fragment complexes (26)