Fig. 2: Structure and fluorescence properties of 1,3a,6a-triazapentalene and the expansion to the most compact fluorescent labeling reagent. | Communications Chemistry

Fig. 2: Structure and fluorescence properties of 1,3a,6a-triazapentalene and the expansion to the most compact fluorescent labeling reagent.

From: Development of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorescent labeling reagent

Fig. 2

a Previous work; structure of 1,3a,6a-triazapentalene (TAP) and the fluorescence properties of TAP that change according to the inductive effect at the C2-position. b This work; the ketone group was observed to be a more photostable functional group than alkyl, amide, or ester. To use the ketone group as a compact fluorescent labeling reagent, the application of a vinyl ketone group was planned with a view to the labeling of the thiol group by the particular 1,4-addition reaction of thiol groups.

Back to article page