Fig. 1: General summary of the study.
From: Optical and theoretical study of strand recognition by nucleic acid probes
a Representation of the assays conducted (FRET, mesoscopic modelling, UV Tm, and CD) and sample variables: additives, duplex and additive concentrations and oligonucleotide sequence content. PEG = polyethylene glycol 2000. Chemical structure of locked nucleic acid monomer, LNA, with B standing for nucleobase b Illustration of probes with RNA targets organized in three groups based on the targeted oncogene: BRAF, KRAS, and EGFR, c Chemical structures of FRET pairs.
