Fig. 4: Free energy landscape (FEL) of KID and KIX binding process. | Communications Chemistry

Fig. 4: Free energy landscape (FEL) of KID and KIX binding process.

From: Phosphorylation regulates the binding of intrinsically disordered proteins via a flexible conformation selection mechanism

Fig. 4: Free energy landscape (FEL) of KID and KIX binding process.

The FEL is the function of the KID-KIX distance and native contacts number, which formed in pKID-KIX. Representative structures of states E and I are shown. The structure of KID-KIX complex derived from pKID-KIX crystal structure and shown by surface in KID-KIX complex, KID color in dark-gray and KIX color in gray. The structures of KID in major states was shown in ribbon and αA region color in blue, αB region color in red. The coordinates in PDB format of the representative structures are given in Supplementary Data 2.

Back to article page