Fig. 6: Water thermodynamic calculations for the solvation of the aromatic cage of KDM5A PHD3 fingers.

a Wild-type KDM5A; b 5F-KDM5A; c 6F-KDM5A; d 5,6diF-KDM5A; e Thermodynamic parameters for the solvation of the aromatic cages of four KDM5A proteins used in this study.