Fig. 4: Preliminary mechanistic investigation. | Communications Chemistry

Fig. 4: Preliminary mechanistic investigation.

From: Radical hydrodifluoromethylation of unsaturated C−C bonds via an electroreductively triggered two-pronged approach

Fig. 4

A A significant amount of deuterium incorporation was observed upon employment of D2O in under optimized reaction conditions (Eq. 1). The reaction with piperidine-d11 result in low deuterium incorporation (Eq. 2). B Vinyl cyclopropane 6a with higher ring opening rate constant (kPh = ~108 s−1) underwent rupture of the three-membered ring (8a), while the cyclopropyl ring in 6b (kH = ~105 s−1) remained intact after electrolysis.

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